BDBM504402 US11040984, Compound 2

SMILES COc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1N1CC2(CCN(C)CC2)OC1=O

InChI Key InChIKey=PQHBTLFVLADREW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 504402   

TargetEpidermal growth factor receptor [L858R](Homo sapiens (Human))
Medshine Discovery

US Patent
LigandPNGBDBM504402(US11040984, Compound 2)
Affinity DataIC50:  48.1nMAssay Description:Buffer formulation: a buffer consisted of 50 mM HEPES (pH 7.5), 0.01% BSA, 5 mM MgCl2, 0.1 mM Orthovanadate. After the buffer was formulated, an enzy...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor [1-745,751-1210](Homo sapiens (Human))
Medshine Discovery

US Patent
LigandPNGBDBM504402(US11040984, Compound 2)
Affinity DataIC50:  16.5nMAssay Description:Buffer formulation: a buffer consisted of 50 mM HEPES (pH 7.5), 0.01% BSA, 5 mM MgCl2, 0.1 mM Orthovanadate. After the buffer was formulated, an enzy...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent