BDBM504405 US11040984, Compound 4

SMILES COc1cc2ncnc(Nc3cccc(Cl)c3OC)c2cc1N1CC2(CCN(C)CC2)OC1=O

InChI Key InChIKey=UJPBOUWNIKXHIJ-UHFFFAOYSA-N

Data  2 IC50

Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 504405   

TargetEpidermal growth factor receptor [L858R](Homo sapiens (Human))
MEDSHINE DISCOVERY INC.

US Patent
LigandPNGBDBM504405(US11040984, Compound 4)
Show SMILES COc1cc2ncnc(Nc3cccc(Cl)c3OC)c2cc1N1CC2(CCN(C)CC2)OC1=O
Show InChI InChI=1S/C24H26ClN5O4/c1-29-9-7-24(8-10-29)13-30(23(31)34-24)19-11-15-18(12-20(19)32-2)26-14-27-22(15)28-17-6-4-5-16(25)21(17)33-3/h4-6,11-12,14H,7-10,13H2,1-3H3,(H,26,27,28)
Affinity DataIC50: 30.1nMAssay Description:Buffer formulation: a buffer consisted of 50 mM HEPES (pH 7.5), 0.01% BSA, 5 mM MgCl2, 0.1 mM Orthovanadate. After the buffer was formulated, an enzy...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetEpidermal growth factor receptor [1-745,751-1210](Homo sapiens (Human))
MEDSHINE DISCOVERY INC.

US Patent
LigandPNGBDBM504405(US11040984, Compound 4)
Show SMILES COc1cc2ncnc(Nc3cccc(Cl)c3OC)c2cc1N1CC2(CCN(C)CC2)OC1=O
Show InChI InChI=1S/C24H26ClN5O4/c1-29-9-7-24(8-10-29)13-30(23(31)34-24)19-11-15-18(12-20(19)32-2)26-14-27-22(15)28-17-6-4-5-16(25)21(17)33-3/h4-6,11-12,14H,7-10,13H2,1-3H3,(H,26,27,28)
Affinity DataIC50: 55.4nMAssay Description:Buffer formulation: a buffer consisted of 50 mM HEPES (pH 7.5), 0.01% BSA, 5 mM MgCl2, 0.1 mM Orthovanadate. After the buffer was formulated, an enzy...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid