BDBM50440721 CHEMBL2431075
SMILES C[C@H]([C@@H]1N=C(c2c(C)c(C)sc2-c2c(C)noc12)c1ccc(cc1)C#N)C(N)=O
InChI Key InChIKey=AVHQENNJMVDDPS-ZMZPIMSZSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50440721
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Constellation Pharmaceuticals
Curated by ChEMBL
Constellation Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 250nMAssay Description:Inhibition of His-FLAG-tagged BRD4 binding domain1 (unknown origin) binding to H4-TetraAc-biotin peptide after 20 mins by AlphaLISAMore data for this Ligand-Target Pair
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Constellation Pharmaceuticals
Curated by ChEMBL
Constellation Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 710nMAssay Description:Inhibition of BRD4 in human Raji cells assessed as reduction of MYC expression after 4 hrsMore data for this Ligand-Target Pair