BDBM50443232 CHEMBL3086883
SMILES Cc1cc(N=Nc2ccc(cc2)S(=O)(=O)Nc2ccccn2)c(N)cc1O
InChI Key InChIKey=DZTGIRNXWSZBIM-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 16 hits for monomerid = 50443232
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Icahn School Of Medicine At Mount Sinai
Curated by ChEMBL
Icahn School Of Medicine At Mount Sinai
Curated by ChEMBL
Affinity DataKi: 85nMAssay Description:Displacement of fluorescein-labeled MS574 from recombinant human BRD4 BrD1 after 1 hr by fluorescence anisotropy assayMore data for this Ligand-Target Pair
3D Structure (crystal)TargetBromodomain-containing protein 4(Homo sapiens (Human))
Icahn School Of Medicine At Mount Sinai
Curated by ChEMBL
Icahn School Of Medicine At Mount Sinai
Curated by ChEMBL
Affinity DataKi: <85nMAssay Description:Inhibition of human 6x-His-tagged BRD4 bromodomain 1 expressed in Escherichia coliMore data for this Ligand-Target Pair
TargetBromodomain-containing protein 3(Homo sapiens (Human))
University Of Minnesota
Curated by ChEMBL
University Of Minnesota
Curated by ChEMBL
Affinity DataKi: 100nMAssay Description:Inhibition of human 6x-His-tagged BRD3 bromodomain 1 expressed in Escherichia coliMore data for this Ligand-Target Pair
TargetBromodomain-containing protein 3(Homo sapiens (Human))
University Of Minnesota
Curated by ChEMBL
University Of Minnesota
Curated by ChEMBL
Affinity DataKi: 100nMAssay Description:Displacement of fluorescein-labeled MS574 from recombinant human BRD3 BrD1 after 1 hr by fluorescence anisotropy assayMore data for this Ligand-Target Pair
TargetBromodomain-containing protein 3(Homo sapiens (Human))
University Of Minnesota
Curated by ChEMBL
University Of Minnesota
Curated by ChEMBL
Affinity DataKi: 140nMAssay Description:Displacement of fluorescein-labeled MS574 from recombinant human BRD3 BrD2 after 1 hr by fluorescence anisotropy assayMore data for this Ligand-Target Pair
TargetBromodomain-containing protein 3(Homo sapiens (Human))
University Of Minnesota
Curated by ChEMBL
University Of Minnesota
Curated by ChEMBL
Affinity DataKi: 140nMAssay Description:Inhibition of human 6x-His-tagged BRD3 bromodomain 2 expressed in Escherichia coliMore data for this Ligand-Target Pair
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Icahn School Of Medicine At Mount Sinai
Curated by ChEMBL
Icahn School Of Medicine At Mount Sinai
Curated by ChEMBL
Affinity DataKi: 340nMAssay Description:Displacement of fluorescein-labeled MS574 from recombinant human BRD4 BrD2 after 1 hr by fluorescence anisotropy assayMore data for this Ligand-Target Pair
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Icahn School Of Medicine At Mount Sinai
Curated by ChEMBL
Icahn School Of Medicine At Mount Sinai
Curated by ChEMBL
Affinity DataKi: 340nMAssay Description:Inhibition of human 6x-His-tagged BRD4 bromodomain 2 expressed in Escherichia coliMore data for this Ligand-Target Pair
TargetCREB-binding protein(Homo sapiens (Human))
Icahn School Of Medicine At Mount Sinai
Curated by ChEMBL
Icahn School Of Medicine At Mount Sinai
Curated by ChEMBL
Affinity DataKi: 2.18E+3nMAssay Description:Displacement of fluorescein-labeled MS226 from recombinant human CBP bromodomain after 1 hr by fluorescence anisotropy assayMore data for this Ligand-Target Pair
TargetBromodomain-containing protein 7(Homo sapiens (Human))
Icahn School Of Medicine At Mount Sinai
Curated by ChEMBL
Icahn School Of Medicine At Mount Sinai
Curated by ChEMBL
Affinity DataKi: 2.72E+3nMAssay Description:Displacement of fluorescein-labeled MS226 from recombinant human BRD7 after 1 hr by fluorescence anisotropy assayMore data for this Ligand-Target Pair
TargetBromodomain adjacent to zinc finger domain protein 2B(Homo sapiens (Human))
Icahn School Of Medicine At Mount Sinai
Curated by ChEMBL
Icahn School Of Medicine At Mount Sinai
Curated by ChEMBL
Affinity DataKi: 3.29E+3nMAssay Description:Displacement of fluorescein-labeled MS239 from recombinant human BAZ2b after 1 hr by fluorescence anisotropy assayMore data for this Ligand-Target Pair
TargetHistone acetyltransferase KAT2B(Homo sapiens (Human))
Icahn School Of Medicine At Mount Sinai
Curated by ChEMBL
Icahn School Of Medicine At Mount Sinai
Curated by ChEMBL
Affinity DataKi: 5.52E+3nMAssay Description:Displacement of fluorescein-labeled MS239 from recombinant human PCAF after 1 hr by fluorescence anisotropy assayMore data for this Ligand-Target Pair
TargetNucleosome-remodeling factor subunit BPTF(Homo sapiens (Human))
Icahn School Of Medicine At Mount Sinai
Curated by ChEMBL
Icahn School Of Medicine At Mount Sinai
Curated by ChEMBL
Affinity DataKi: 6.06E+3nMAssay Description:Displacement of fluorescein-labeled MS239 from recombinant human BPTF after 1 hr by fluorescence anisotropy assayMore data for this Ligand-Target Pair
TargetTranscription activator BRG1(Homo sapiens (Human))
Icahn School Of Medicine At Mount Sinai
Curated by ChEMBL
Icahn School Of Medicine At Mount Sinai
Curated by ChEMBL
Affinity DataKi: 7.97E+3nMAssay Description:Displacement of fluorescein-labeled MS239 from recombinant human SMARCA4 bromodomain after 1 hr by fluorescence anisotropy assayMore data for this Ligand-Target Pair
TargetBromodomain-containing protein 4(Mus musculus)
Icahn School Of Medicine At Mount Sinai
Curated by ChEMBL
Icahn School Of Medicine At Mount Sinai
Curated by ChEMBL
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition of BRD4 in LPS-stimulated mouse RAW264.7 cells assessed as inhibition of NF-kappaB-mediated nitric oxide production preincubated for 30 mi...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 4(Mus musculus)
Icahn School Of Medicine At Mount Sinai
Curated by ChEMBL
Icahn School Of Medicine At Mount Sinai
Curated by ChEMBL
Affinity DataIC50: 4.90E+3nMAssay Description:Inhibition of BRD4 in LPS-stimulated mouse RAW264.7 cells assessed as inhibition of NF-kappaB-mediated IL-6 expression preincubated for 30 mins follo...More data for this Ligand-Target Pair