BDBM50443651 CHEMBL3093073

SMILES CC(C)[C@@H](Nc1nnc(o1)-c1c[nH]c2ncccc12)c1ccccc1

InChI Key InChIKey=IDWMTFSSSIBSAB-MRXNPFEDSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50443651   

LigandPNGBDBM50443651(CHEMBL3093073)
Affinity DataIC50:  2nMAssay Description:Inhibition of Cdc7/Dbf4 (unknown origin)-mediated MCM2 phosphorylation at Ser53 by protein A amplified luminescent proximity homogeneous assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCell division cycle 7-related protein kinase(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50443651(CHEMBL3093073)
Affinity DataIC50:  140nMAssay Description:Inhibition of Cdc7-mediated MCM2 phosphorylation at Ser53 in human HCT116 cells after 14 hrs by immunostaining assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50443651(CHEMBL3093073)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of CDK2/cyclin E (unknown origin) using ULight peptide as substrate by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed