BDBM504446 US11034715, Cpd. # 198

SMILES Nc1nc(Cl)nc2n(cnc12)[C@@H]1O[C@H](COC(Cc2ccc(OCc3ccccc3)cc2)(C(O)=O)c2nn[nH]n2)[C@@H](O)[C@H]1O

InChI Key

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 504446   

Target5'-nucleotidase(Homo sapiens (Human))
Calithera Biosciences

US Patent
LigandPNGBDBM504446(US11034715, Cpd. # 198)
Affinity DataIC50:  175nMAssay Description:The ability of compounds to inhibit endogenous, cell-bound CD73 enzyme activity was demonstrated using SK-MEL-28 cells, which express CD73 on their s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5'-nucleotidase(Homo sapiens (Human))
Calithera Biosciences

US Patent
LigandPNGBDBM504446(US11034715, Cpd. # 198)
Affinity DataIC50:  29nMAssay Description:For measurements of soluble CD73 enzyme activity, recombinant CD73 was obtained from R&D Systems, Cat. No. 5795-EN-010. Serial dilutions of test comp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent