BDBM50446401 CHEMBL3109656
SMILES Oc1cc(cc2cc(NC(=O)Nc3ccc4c(O)cc(cc4c3)S([O-])(=O)=O)ccc12)S([O-])(=O)=O
InChI Key InChIKey=PCGISRHGYLRXSR-UHFFFAOYSA-L
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50446401
TargetProtein arginine N-methyltransferase 1 [11-371](Homo sapiens (Human))
Icahn School Of Medicine At Mount Sinai
Curated by ChEMBL
Icahn School Of Medicine At Mount Sinai
Curated by ChEMBL
Affinity DataIC50: 8.80E+3nMAssay Description:Inhibition of recombinant human PRMT1 using GST-Npl3 as substrate incubated for 15 mins prior to protein addition measured after 1 hr by colorimetric...More data for this Ligand-Target Pair
TargetProtein arginine N-methyltransferase 1(Homo sapiens)
Ningxia Medical University
Curated by ChEMBL
Ningxia Medical University
Curated by ChEMBL
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged PRMT1 (2 to end residues) expressed in baculovirus infected Sf9 insect cells using biotinylated...More data for this Ligand-Target Pair
TargetProtein arginine N-methyltransferase 1 [11-371](Homo sapiens (Human))
Icahn School Of Medicine At Mount Sinai
Curated by ChEMBL
Icahn School Of Medicine At Mount Sinai
Curated by ChEMBL
Affinity DataIC50: 8.80E+3nMAssay Description:Inhibition of recombinant human PRMT1 expressed in Escherichia coli using histone H4 peptide as substrate by chemiluminescence assayMore data for this Ligand-Target Pair
TargetProtein arginine N-methyltransferase 1 [11-371](Homo sapiens (Human))
Icahn School Of Medicine At Mount Sinai
Curated by ChEMBL
Icahn School Of Medicine At Mount Sinai
Curated by ChEMBL
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of PRMT1 (unknown origin) using biotinylated histone H4-derived peptide as substrate after 60 mins by AlphaLISA assayMore data for this Ligand-Target Pair