BDBM504473 N-(1-(3-((2-(2-((2-(2,6- dioxopiperidin-3-yl)-1,3- dioxoisoindolin-5- yl)oxy)ethoxy)ethyl)(methyl) amino)phenyl)-5-fluoro-1H- benzo[d]imidazol-2-yl)-3- (trifluoromethyl)benzamide::US11065231, Example 51

SMILES CN(CCOCCOc1ccc2C(=O)N(C3CCC(=O)NC3=O)C(=O)c2c1)c1cccc(c1)-n1c(NC(=O)c2cccc(c2)C(F)(F)F)nc2cc(F)ccc12

InChI Key InChIKey=BYFJOHHHGFFGAZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 504473   

TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Arvinas Operations

US Patent
LigandPNGBDBM504473(N-(1-(3-((2-(2-((2-(2,6- dioxopiperidin-3-yl)-1,3-...)
Affinity DataIC50: >1.00E+3nMAssay Description:A Z′-Lyte assay based on a fluorescence resonance energy transfer (FRET) readout was developed for measuring IRAK4-dependent phosphorylation of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent