BDBM504487 N-(2-(1-((1-(2-((2-(2,6- dioxopiperidin-3-yl)-1,3- dioxoisoindolin-5- yl)oxy)ethyl)piperadin-4- yl)methyl)piperidin-4-yl)-6- methoxy-2H-indazol-5-yl)-6- (trifluoromethyl)picolinamide::US11065231, Example 63

SMILES COc1cc2nn(cc2cc1NC(=O)c1cccc(n1)C(F)(F)F)C1CCN(CC2CCN(CCOc3ccc4C(=O)N(C5CCC(=O)NC5=O)C(=O)c4c3)CC2)CC1

InChI Key InChIKey=BAFBCLQIBRFNCX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 504487   

TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Arvinas Operations

US Patent
LigandPNGBDBM504487(N-(2-(1-((1-(2-((2-(2,6- dioxopiperidin-3-yl)-1,3-...)
Affinity DataIC50: <30nMAssay Description:A Z′-Lyte assay based on a fluorescence resonance energy transfer (FRET) readout was developed for measuring IRAK4-dependent phosphorylation of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent