BDBM504489 N-(5-((4-(2-(2-(2-((2-(2,6- dioxopiperidin-3-yl)-1,3- dioxoisoindolin-4- yl)amino)ethoxy)ethoxy)ethyl) piperazin-1-yl)methyl)-1- ((1s,4s)-4- (hydroxymethyl)cyclohexyl)- 1H-benzo[d]imidazol-2-yl)- 3- (trifluoromethyl)benzamide::US11065231, Example 66

SMILES OC[C@H]1CCC(CC1)n1c(NC(=O)c2cccc(c2)C(F)(F)F)nc2cc(CN3CCN(CCOCCOCCNc4cccc5C(=O)N(C6CCC(=O)NC6=O)C(=O)c45)CC3)ccc12

InChI Key InChIKey=MTQSWFCJLVMBRF-GYWBCSHJSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 504489   

TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Arvinas Operations

US Patent
LigandPNGBDBM504489(N-(5-((4-(2-(2-(2-((2-(2,6- dioxopiperidin-3-yl)-1...)
Affinity DataIC50: <30nMAssay Description:A Z′-Lyte assay based on a fluorescence resonance energy transfer (FRET) readout was developed for measuring IRAK4-dependent phosphorylation of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent