BDBM504504 N-(5,5-difluoropiperidin-3-yl)-2-{5-[(3- ethoxypyridin-2-yl)oxy]pyridin-3- yl}pyrimidine-5-carboxamide::US11065249, Example 17::US11471458, Example 17::US20230405002, Example 17

SMILES CCOc1cccnc1Oc1cncc(c1)-c1ncc(cn1)C(=O)NC1CNCC(F)(F)C1

InChI Key InChIKey=STEOFTXCZZHZJZ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 504504   

TargetDiacylglycerol O-acyltransferase 2(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM504504(N-(5,5-difluoropiperidin-3-yl)-2-{5-[(3- ethoxypyr...)
Affinity DataIC50:  230nMAssay Description:For determination of IC50 values, the reactions were carried out in 384-well white polypropylene plates (Nunc) in a total volume of 20 μL. To 1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDiacylglycerol O-acyltransferase 2(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM504504(N-(5,5-difluoropiperidin-3-yl)-2-{5-[(3- ethoxypyr...)
Affinity DataIC50:  230nMAssay Description:For determination of IC50 values, the reactions were carried out in 384-well white polypropylene plates (Nunc) in a total volume of 20 μL. To 1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDiacylglycerol O-acyltransferase 2(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM504504(N-(5,5-difluoropiperidin-3-yl)-2-{5-[(3- ethoxypyr...)
Affinity DataIC50:  230nMAssay Description:For determination of IC50 values, the reactions were carried out in 384-well white polypropylene plates (Nunc) in a total volume of 20 μL. To 1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent