BDBM504507 US11065249, Example 20::US11471458, Example 20::rac-2-{5-[(3-ethoxypyridin-2- yl)oxy]pyridin-3-yl}-N-[(3R,4R)-4- methylpiperidin-3-yl]pyrimidine-5- carboxamide, trifluoroacetate salt

SMILES CCOc1cccnc1Oc1cncc(c1)-c1ncc(cn1)C(=O)N[C@H]1CNCC[C@H]1C

InChI Key InChIKey=LRSAMYOELHWQFE-BEFAXECRSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 504507   

TargetDiacylglycerol O-acyltransferase 2(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM504507(US11065249, Example 20 | US11471458, Example 20 | ...)
Affinity DataIC50:  2.10E+3nMAssay Description:For determination of IC50 values, the reactions were carried out in 384-well white polypropylene plates (Nunc) in a total volume of 20 μL. To 1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDiacylglycerol O-acyltransferase 2(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM504507(US11065249, Example 20 | US11471458, Example 20 | ...)
Affinity DataIC50:  2.10E+3nMAssay Description:For determination of IC50 values, the reactions were carried out in 384-well white polypropylene plates (Nunc) in a total volume of 20 μL. To 1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent