BDBM50451023 MESULERGINE

SMILES [H][C@@]12Cc3cn(C)c4cccc(c34)[C@@]1([H])C[C@H](CNS(=O)(=O)N(C)C)CN2C

InChI Key InChIKey=IEVQSJGJLKPGSL-MZMPZRCHSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50451023   

Target5-hydroxytryptamine receptor 2C(Rattus norvegicus (Rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50451023(MESULERGINE)
Affinity DataKi:  0.730nMAssay Description:Ability to displace [3H]mesulergine bound to 5-hydroxytryptamine 2C receptor in rat cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Rattus norvegicus (Rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50451023(MESULERGINE)
Affinity DataKi:  5.20nMAssay Description:The compound was tested for their binding affinity towards 5-hydroxytryptamine 2C receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50451023(MESULERGINE)
Affinity DataIC50:  1.90nMAssay Description:Inhibitory concentration against human Adenosine A3 receptor expressed in HEK293 cells using 0.1 nM [3H]AB-MECAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50451023(MESULERGINE)
Affinity DataIC50:  2.10nMAssay Description:Inhibition of radiolabeled [3H]-Zacopride ligand binding to 5-hydroxytryptamine 3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed