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BDBM50453069 CHEMBL2367764

SMILES: [H][C@]12Cc3ccc(O)cc3[C@@](C)(CCN1C[C@@H]1CCC(=O)O1)[C@H]2C

InChI Key: InChIKey=HHASRPPPJAXSNL-FRXJQCMVSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50453069   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
mu/kappa opioid receptor


(Cavia porcellus (domestic guinea pig))
BDBM50453069
PNG
(CHEMBL2367764)
Show SMILES C[C@H]1[C@H]2Cc3ccc(O)cc3[C@@]1(C)CCN2C[C@@H]1CCC(=O)O1
Show InChI InChI=1S/C19H25NO3/c1-12-17-9-13-3-4-14(21)10-16(13)19(12,2)7-8-20(17)11-15-5-6-18(22)23-15/h3-4,10,12,15,17,21H,5-9,11H2,1-2H3/t12-,15-,17+,19-/m0/s1
PDB

UniProtKB/SwissProt

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PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 7.30n/an/an/an/an/an/a



University of Washington

Curated by ChEMBL


Assay Description
Displacement of [3H]-bremazocine from opioid receptor kappa of guinea pig membrane.


J Med Chem 34: 2438-44 (1991)


Article DOI: 10.1021/jm00112a019
BindingDB Entry DOI: 10.7270/Q2NC605T
More data for this
Ligand-Target Pair