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BDBM50453320 CHEMBL4215162

SMILES: COc1cc(cc(Cl)n1)-c1nc(no1)-c1cc(C(C)C)c2c(C)nn(C)c2n1

InChI Key: InChIKey=PYBOEGZYHNYMBQ-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50453320   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Sphingosine 1-phosphate receptor 2


(Homo sapiens (Human))
BDBM50453320
PNG
(CHEMBL4215162)
Show SMILES COc1cc(cc(Cl)n1)-c1nc(no1)-c1cc(C(C)C)c2c(C)nn(C)c2n1
Show InChI InChI=1S/C19H19ClN6O2/c1-9(2)12-8-13(21-18-16(12)10(3)24-26(18)4)17-23-19(28-25-17)11-6-14(20)22-15(7-11)27-5/h6-9H,1-5H3
NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
Article
n/an/a>1.00E+3n/an/an/an/an/an/a


TBA

Assay Description
Displacement of [32P]S1P from recombinant human S1PR2 expressed in Chem1 cell membranes co-expressing Galpha15 pretreated for 30 mins followed by [32...


Citation and Details

Article DOI: 10.1016/j.bmcl.2017.12.010
BindingDB Entry DOI: 10.7270/Q2S18523
More data for this
Ligand-Target Pair