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BDBM50455955 CHEMBL411467

SMILES: OC(=O)CCC(O)=O.COc1ccccc1C(=O)NC(=O)OC1CC2CCC(C1)N2C

InChI Key: InChIKey=HAMIDLUTHJEBEW-UHFFFAOYSA-N

Data: 1 Kd

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50455955   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor


(Rattus norvegicus-RAT)
BDBM50455955
PNG
(CHEMBL411467)
Show SMILES COc1ccccc1C(=O)NC(=O)OC1CC2CCC(C1)N2C
Show InChI InChI=1S/C17H22N2O4.C4H6O4/c1-19-11-7-8-12(19)10-13(9-11)23-17(21)18-16(20)14-5-3-4-6-15(14)22-2;5-3(6)1-2-4(7)8/h3-6,11-13H,7-10H2,1-2H3,(H,18,20,21);1-2H2,(H,5,6)(H,7,8)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/a 17n/an/an/an/an/a



Wyeth Research

Curated by ChEMBL


Assay Description
In vitro antagonism of the 5-HT-3 receptor determined by inhibition of 5-HT-induced depolarization of the isolated rat vagus nerve.


J Med Chem 35: 1515-20 (1992)


Article DOI: 10.1021/jm00087a003
BindingDB Entry DOI: 10.7270/Q24B32SK
More data for this
Ligand-Target Pair