BDBM504586 6-(3-phenyl-1,2,4- oxadiazol-5-yl)-1- (4-(5- (trifluoromethyl)- 1,2,4-oxadiazol-3- yl)phenyl)piperidin- 2-one::US11066396, Example 44

SMILES FC(F)(F)c1nc(no1)-c1ccc(cc1)N1C(CCCC1=O)c1nc(no1)-c1ccccc1

InChI Key InChIKey=NAOGFHYNRGFHNY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 504586   

TargetHistone deacetylase 6(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM504586(6-(3-phenyl-1,2,4- oxadiazol-5-yl)-1- (4-(5- (trif...)
Affinity DataIC50:  7.30nMAssay Description:HDAC1 and 6 reagents: FLAG-tagged HDACs 1 and 6 were prepared in-house by protein expression in HEK293F cells followed by anti-FLAG affinity purifica...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent