BDBM504624 N-(3- fluorophenyl)-N- ((5-(5- (trifluoromethyl)- 1,2,4-oxadiazol-3- yl)pyridin-2- yl)methyl)tetrahydro- 2H-thiopyran- 4-carboxamide 1,1-dioxide::US11066396, Example 55
SMILES Fc1cccc(c1)N(Cc1ccc(cn1)-c1noc(n1)C(F)(F)F)C(=O)C1CCS(=O)(=O)CC1
InChI Key InChIKey=GOBYTSPLIIKZRF-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 504624
Affinity DataIC50: 8.10nMAssay Description:HDAC1 and 6 reagents: FLAG-tagged HDACs 1 and 6 were prepared in-house by protein expression in HEK293F cells followed by anti-FLAG affinity purifica...More data for this Ligand-Target Pair
Affinity DataIC50: 2.30E+3nMAssay Description:HDAC8 reagents: HDAC8 was purchased from Enzo Life Sciences [catalog #BML-SE145]. Assays were performed with buffer containing 20 mM HEPES, pH 8.0 [B...More data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+3nMAssay Description:HDAC5 reagents: N-terminal GST tagged HDAC5 was purchased from BPS Bioscience [catalog #50045]. Assays were performed with buffer containing 20 mM HE...More data for this Ligand-Target Pair
Affinity DataIC50: 250nMAssay Description:HDAC1 and 6 reagents: FLAG-tagged HDACs 1 and 6 were prepared in-house by protein expression in HEK293F cells followed by anti-FLAG affinity purifica...More data for this Ligand-Target Pair