BDBM50463743 CHEMBL4241370
SMILES CC(C)(CCCCC(=O)NO)Nc1c(Nc2ccc(cc2)C(F)(F)F)c(=O)c1=O
InChI Key InChIKey=RHUMXXCHLQENCI-UHFFFAOYSA-N
Data 16 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 16 hits for monomerid = 50463743
Affinity DataKi: 0.270nMAssay Description:Inhibition of human recombinant HDAC1 using Fluor de Lys as substrate after 2 hrs by fluorescence methodMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Inhibition of human recombinant HDAC1 using fluorogenic HDAC substrate after 15 mins by fluorimetrc methodMore data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Inhibition of human recombinant HDAC10 using fluorogenic HDAC substrate after 45 mins by fluorimetrc methodMore data for this Ligand-Target Pair
Affinity DataKi: 12nMAssay Description:Inhibition of human recombinant HDAC3 using fluorogenic HDAC substrate after 10 mins by spectrophotometric methodMore data for this Ligand-Target Pair
Affinity DataKi: 21nMAssay Description:Inhibition of human recombinant HDAC11 using fluorogenic HDAC substrate class 2a after 30 mins by fluorimetrc methodMore data for this Ligand-Target Pair
Affinity DataKi: 23nMAssay Description:Inhibition of human recombinant HDAC2 using fluorogenic HDAC substrate after 15 mins by fluorimetrc methodMore data for this Ligand-Target Pair
Affinity DataKi: 110nMAssay Description:Inhibition of human recombinant HDAC8 using fluorogenic HDAC substrate after 15 mins by fluorimetrc methodMore data for this Ligand-Target Pair
Affinity DataKi: 130nMAssay Description:Inhibition of human recombinant HDAC6 using fluorogenic HDAC substrate after 30 mins by fluorimetrc methodMore data for this Ligand-Target Pair
Affinity DataKi: 360nMAssay Description:Inhibition of human recombinant HDAC5 using fluorogenic HDAC substrate class 2a after 30 mins by fluorimetrc methodMore data for this Ligand-Target Pair
Affinity DataKi: 1.70E+3nMAssay Description:Inhibition of human recombinant HDAC7 using fluorogenic HDAC substrate class 2a after 45 mins by fluorimetrc methodMore data for this Ligand-Target Pair
Affinity DataKi: 3.40E+3nMAssay Description:Inhibition of human recombinant HDAC4 using fluorogenic HDAC substrate class 2a after 30 mins by fluorimetrc methodMore data for this Ligand-Target Pair
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Nestle Skin Health R&D
Curated by ChEMBL
Nestle Skin Health R&D
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human recombinant SIRT2 using fluoro-lysine sirtuin 2 deacetylase substrate after 60 mins by fluorimetrc methodMore data for this Ligand-Target Pair
TargetNAD-dependent protein deacetylase sirtuin-7(Homo sapiens (Human))
Nestle Skin Health R&D
Curated by ChEMBL
Nestle Skin Health R&D
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of SIRT7 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human recombinant HDAC9 using fluorogenic HDAC substrate class 2a after 30 mins by fluorimetrc methodMore data for this Ligand-Target Pair
TargetNAD-dependent protein deacetylase sirtuin-3, mitochondrial(Homo sapiens (Human))
Nestle Skin Health R&D
Curated by ChEMBL
Nestle Skin Health R&D
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human recombinant SIRT3 using fluoro-lysine sirtuin 2 deacetylase substrate after 45 mins by fluorimetrc methodMore data for this Ligand-Target Pair
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Nestle Skin Health R&D
Curated by ChEMBL
Nestle Skin Health R&D
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human recombinant SIRT1 using fluorogenic HDAC substrate after 20 mins by fluorimetrc methodMore data for this Ligand-Target Pair