BDBM504675 US11066365, Example 51::US11390584, Example 51::rac-(3aR,6aR)-1-([1,1'-biphenyl]- 3-carbonyl)hexahydropyrrolo[3,4- b]pyrrole-5(1H)-carbonitrile

SMILES O=C(N1CC[C@@H]2CN(C[C@H]12)C#N)c1cccc(c1)-c1ccccc1

InChI Key InChIKey=PPHZJOGUKRXUKE-MOPGFXCFSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 504675   

TargetUbiquitin carboxyl-terminal hydrolase 30(Homo sapiens (Human))
Mission Therapeutics

US Patent
LigandPNGBDBM504675(US11066365, Example 51 | US11390584, Example 51 | ...)
Affinity DataIC50: <100nMAssay Description:Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 30(Homo sapiens (Human))
Mission Therapeutics

US Patent
LigandPNGBDBM504675(US11066365, Example 51 | US11390584, Example 51 | ...)
Affinity DataIC50: <100nMAssay Description:USP30 biochemical fluorescence intensity IC50 assay Dilution plates were prepared at 21 times the final concentration (2100 μM for a final conce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent