BDBM504676 (S)-5- (benzo[d]oxazol- 2-yl)-1-(4-(5- (trifluoromethyl)- 1,2,4-oxadiazol-3- yl)phenyl) pyrrolidin-2-one::US11066396, Example 104
SMILES FC(F)(F)c1nc(no1)-c1ccc(cc1)N1[C@@H](CCC1=O)c1nc2ccccc2o1
InChI Key InChIKey=ITRLKPUDLMGBGC-AWEZNQCLSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 504676
Affinity DataIC50: 7.10nMAssay Description:HDAC1 and 6 reagents: FLAG-tagged HDACs 1 and 6 were prepared in-house by protein expression in HEK293F cells followed by anti-FLAG affinity purifica...More data for this Ligand-Target Pair
Affinity DataIC50: 440nMAssay Description:HDAC8 reagents: HDAC8 was purchased from Enzo Life Sciences [catalog #BML-SE145]. Assays were performed with buffer containing 20 mM HEPES, pH 8.0 [B...More data for this Ligand-Target Pair
Affinity DataIC50: 120nMAssay Description:HDAC1 and 6 reagents: FLAG-tagged HDACs 1 and 6 were prepared in-house by protein expression in HEK293F cells followed by anti-FLAG affinity purifica...More data for this Ligand-Target Pair