BDBM504678 (S)-5-(1H- benzo[d]imidazol- 2-yl)-1-(2-fluoro- 4-(5- (trifluoromethyl)- 1,2,4-oxadiazol-3- yl)phenyl) pyrrolidin-2-one::US11066396, Example 106

SMILES Fc1cc(ccc1N1[C@@H](CCC1=O)c1nc2ccccc2[nH]1)-c1noc(n1)C(F)(F)F

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 504678   

TargetHistone deacetylase 6(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM504678((S)-5-(1H- benzo[d]imidazol- 2-yl)-1-(2-fluoro- 4-...)
Affinity DataIC50:  4.10nMAssay Description:HDAC1 and 6 reagents: FLAG-tagged HDACs 1 and 6 were prepared in-house by protein expression in HEK293F cells followed by anti-FLAG affinity purifica...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent