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BDBM50471487 CHEMBL436075

SMILES: [H][C@@]12CN(C[C@H]1c1nsnc1SCCCC(F)(F)F)CCC2

InChI Key: InChIKey=QROOTTZWVVRLNV-NXEZZACHSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50471487   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Muscarinic acetylcholine receptor


(RAT)
BDBM50471487
PNG
(CHEMBL436075)
Show SMILES FC(F)(F)CCCSc1nsnc1[C@@H]1CN2C[C@H]1CCC2
Show InChI InChI=1S/C13H18F3N3S2/c14-13(15,16)4-2-6-20-12-11(17-21-18-12)10-8-19-5-1-3-9(10)7-19/h9-10H,1-8H2/t9-,10-/m1/s1
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem
PubMed
0.330n/an/an/an/an/an/an/an/a



Lilly Research Laboratories

Curated by ChEMBL


Assay Description
Binding affinity against Muscarinic acetylcholine receptors using [3H]oxotremorine-M as radioligand in rat cortex


J Med Chem 40: 538-46 (1997)


BindingDB Entry DOI: 10.7270/Q2SQ934F
More data for this
Ligand-Target Pair