BDBM50477854 CHEMBL253342

SMILES Oc1ccc2CN(Cc3ccc(F)c(Cl)c3)C(=O)c2c1O

InChI Key InChIKey=HBQNDWWKBFCHMH-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50477854   

TargetIntegrase(Human immunodeficiency virus 1)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50477854(CHEMBL253342)
Show SMILES Oc1ccc2CN(Cc3ccc(F)c(Cl)c3)C(=O)c2c1O
Show InChI InChI=1S/C15H11ClFNO3/c16-10-5-8(1-3-11(10)17)6-18-7-9-2-4-12(19)14(20)13(9)15(18)21/h1-5,19-20H,6-7H2
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of recombinant HIV1 integrase-mediated 3'-processing activity in presence of magnesiumMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetIntegrase(Human immunodeficiency virus 1)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50477854(CHEMBL253342)
Show SMILES Oc1ccc2CN(Cc3ccc(F)c(Cl)c3)C(=O)c2c1O
Show InChI InChI=1S/C15H11ClFNO3/c16-10-5-8(1-3-11(10)17)6-18-7-9-2-4-12(19)14(20)13(9)15(18)21/h1-5,19-20H,6-7H2
Affinity DataIC50: 160nMAssay Description:Inhibition of recombinant HIV1 integrase strand transfer activity in presence of magnesiumMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB