BDBM50478100 CHEMBL252036::GS-9148

SMILES Nc1ncnc2n(cnc12)[C@@H]1O[C@H](OCP(O)(O)=O)C=C1F

InChI Key InChIKey=MPSGQQOHTJUJKB-QUBYGPBYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50478100   

TargetReverse transcriptase(Human immunodeficiency virus 1)
Gilead Science, Inc

Curated by ChEMBL
LigandPNGBDBM50478100(CHEMBL252036 | GS-9148)
Show SMILES Nc1ncnc2n(cnc12)[C@@H]1O[C@H](OCP(O)(O)=O)C=C1F
Show InChI InChI=1S/C10H11FN5O5P/c11-5-1-6(20-4-22(17,18)19)21-10(5)16-3-15-7-8(12)13-2-14-9(7)16/h1-3,6,10H,4H2,(H2,12,13,14)(H2,17,18,19)/t6-,10+/m0/s1
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition on HIV1 reverse transcriptase p66/p51More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetReverse transcriptase(Human immunodeficiency virus 1)
Gilead Science, Inc

Curated by ChEMBL
LigandPNGBDBM50478100(CHEMBL252036 | GS-9148)
Show SMILES Nc1ncnc2n(cnc12)[C@@H]1O[C@H](OCP(O)(O)=O)C=C1F
Show InChI InChI=1S/C10H11FN5O5P/c11-5-1-6(20-4-22(17,18)19)21-10(5)16-3-15-7-8(12)13-2-14-9(7)16/h1-3,6,10H,4H2,(H2,12,13,14)(H2,17,18,19)/t6-,10+/m0/s1
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of wild type HIV 3B reverse transcriptase in MT2 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB