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BDBM50478802 CHEMBL477115

SMILES: COc1ccc(cc1)-c1cnnn1-c1cc(OC)c(OC)c(OC)c1

InChI Key: InChIKey=VYIKEPOZDAQBBG-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50478802   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tubulin beta chain


(Sus scrofa)
BDBM50478802
PNG
(CHEMBL477115)
Show SMILES COc1ccc(cc1)-c1cnnn1-c1cc(OC)c(OC)c(OC)c1
Show InChI InChI=1S/C18H19N3O4/c1-22-14-7-5-12(6-8-14)15-11-19-20-21(15)13-9-16(23-2)18(25-4)17(10-13)24-3/h5-11H,1-4H3
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 7.00E+3n/an/an/an/an/an/a



University of Oslo

Curated by ChEMBL


Assay Description
Inhibition of pig brain tubulin polymerization


Bioorg Med Chem 16: 4829-38 (2008)


Article DOI: 10.1016/j.bmc.2008.03.049
BindingDB Entry DOI: 10.7270/Q2CZ39XN
More data for this
Ligand-Target Pair