BDBM50481424 CHEMBL605779::ZINC 01078518

SMILES: Cc1ccc(Cl)cc1NS(=O)(=O)c1ccc(NS(=O)(=O)c2ccc3ccccc3c2)cc1

InChI Key: InChIKey=HJHVDDJLCIDJRS-UHFFFAOYSA-N

Data: 2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50481424   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Genome polyprotein (Dengue virus type 2)	BDBM50481424 (CHEMBL605779 | ZINC 01078518) Show SMILES Cc1ccc(Cl)cc1NS(=O)(=O)c1ccc(NS(=O)(=O)c2ccc3ccccc3c2)cc1 Show InChI InChI=1S/C23H19ClN2O4S2/c1-16-6-8-19(24)15-23(16)26-31(27,28)21-12-9-20(10-13-21)25-32(29,30)22-11-7-17-4-2-3-5-18(17)14-22/h2-15,25-26H,1H3	PDB UniProtKB/SwissProt GoogleScholar	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.42E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Basel Curated by ChEMBL					Assay Description Inhibition of Dengue virus type 2 NS5 RNA methyltransferase RNA site with 0.1 % TX100				J Med Chem 53: 1483-95 (2010) Article DOI: 10.1021/jm900776m BindingDB Entry DOI: 10.7270/Q2ST7SNQ
					More data for this Ligand-Target Pair
Genome polyprotein (Dengue virus type 2)	BDBM50481424 (CHEMBL605779 | ZINC 01078518) Show SMILES Cc1ccc(Cl)cc1NS(=O)(=O)c1ccc(NS(=O)(=O)c2ccc3ccccc3c2)cc1 Show InChI InChI=1S/C23H19ClN2O4S2/c1-16-6-8-19(24)15-23(16)26-31(27,28)21-12-9-20(10-13-21)25-32(29,30)22-11-7-17-4-2-3-5-18(17)14-22/h2-15,25-26H,1H3	PDB UniProtKB/SwissProt GoogleScholar	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	9.28E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Basel Curated by ChEMBL					Assay Description Inhibition of Dengue virus type 2 NS5 RNA methyltransferase RNA site				J Med Chem 53: 1483-95 (2010) Article DOI: 10.1021/jm900776m BindingDB Entry DOI: 10.7270/Q2ST7SNQ
					More data for this Ligand-Target Pair