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BDBM50481424 CHEMBL605779::ZINC 01078518

SMILES: Cc1ccc(Cl)cc1NS(=O)(=O)c1ccc(NS(=O)(=O)c2ccc3ccccc3c2)cc1

InChI Key: InChIKey=HJHVDDJLCIDJRS-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB:
Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50481424   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Genome polyprotein


(Dengue virus type 2)
BDBM50481424
PNG
(CHEMBL605779 | ZINC 01078518)
Show SMILES Cc1ccc(Cl)cc1NS(=O)(=O)c1ccc(NS(=O)(=O)c2ccc3ccccc3c2)cc1
Show InChI InChI=1S/C23H19ClN2O4S2/c1-16-6-8-19(24)15-23(16)26-31(27,28)21-12-9-20(10-13-21)25-32(29,30)22-11-7-17-4-2-3-5-18(17)14-22/h2-15,25-26H,1H3
PDB

UniProtKB/SwissProt

GoogleScholar
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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 6.42E+4n/an/an/an/an/an/a



University of Basel

Curated by ChEMBL


Assay Description
Inhibition of Dengue virus type 2 NS5 RNA methyltransferase RNA site with 0.1 % TX100


J Med Chem 53: 1483-95 (2010)


Article DOI: 10.1021/jm900776m
BindingDB Entry DOI: 10.7270/Q2ST7SNQ
More data for this
Ligand-Target Pair
Genome polyprotein


(Dengue virus type 2)
BDBM50481424
PNG
(CHEMBL605779 | ZINC 01078518)
Show SMILES Cc1ccc(Cl)cc1NS(=O)(=O)c1ccc(NS(=O)(=O)c2ccc3ccccc3c2)cc1
Show InChI InChI=1S/C23H19ClN2O4S2/c1-16-6-8-19(24)15-23(16)26-31(27,28)21-12-9-20(10-13-21)25-32(29,30)22-11-7-17-4-2-3-5-18(17)14-22/h2-15,25-26H,1H3
PDB

UniProtKB/SwissProt

GoogleScholar
Purchase

PC cid
PC sid
UniChem
Article
PubMed
n/an/a 9.28E+3n/an/an/an/an/an/a



University of Basel

Curated by ChEMBL


Assay Description
Inhibition of Dengue virus type 2 NS5 RNA methyltransferase RNA site


J Med Chem 53: 1483-95 (2010)


Article DOI: 10.1021/jm900776m
BindingDB Entry DOI: 10.7270/Q2ST7SNQ
More data for this
Ligand-Target Pair