BDBM50485671 ADOCIAQUINONE A::Adociaquinones A

SMILES C[C@@]12CCCc3coc(c13)C(=O)c1cc3C(O)=C4C(=NCCS4(=O)=O)C(=O)c3cc21

InChI Key InChIKey=XMMUEJLHMRZENL-QFIPXVFZSA-N

Data  2 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50485671   

TargetEndothelial PAS domain-containing protein 1/Hypoxia-inducible factor 1-alpha(Homo sapiens (Human))
University of Mississippi

Curated by ChEMBL
LigandPNGBDBM50485671(ADOCIAQUINONE A | Adociaquinones A)
Show SMILES C[C@@]12CCCc3coc(c13)C(=O)c1cc3C(O)=C4C(=NCCS4(=O)=O)C(=O)c3cc21
Show InChI InChI=1S/C22H17NO6S/c1-22-4-2-3-10-9-29-20(15(10)22)18(25)13-7-11-12(8-14(13)22)17(24)16-21(19(11)26)30(27,28)6-5-23-16/h7-9,26H,2-6H2,1H3/t22-/m0/s1
Affinity DataIC50: 200nMAssay Description:Inhibition of 1,10-phenanthroline-induced HIF1 activation in human T47D cells after 16 hrs by HRE3-TK-luciferase reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetEndothelial PAS domain-containing protein 1/Hypoxia-inducible factor 1-alpha(Homo sapiens (Human))
University of Mississippi

Curated by ChEMBL
LigandPNGBDBM50485671(ADOCIAQUINONE A | Adociaquinones A)
Show SMILES C[C@@]12CCCc3coc(c13)C(=O)c1cc3C(O)=C4C(=NCCS4(=O)=O)C(=O)c3cc21
Show InChI InChI=1S/C22H17NO6S/c1-22-4-2-3-10-9-29-20(15(10)22)18(25)13-7-11-12(8-14(13)22)17(24)16-21(19(11)26)30(27,28)6-5-23-16/h7-9,26H,2-6H2,1H3/t22-/m0/s1
Affinity DataIC50: 6.40E+3nMAssay Description:Inhibition of hypoxia-induced HIF1 activation in human T47D cells after 16 hrs by HRE3-TK-luciferase reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid