BDBM50487411 CHEMBL427882::CT-20026

SMILES: CN1CCN(C(=O)C1)c1cnc(NCCNc2ccc(c(N)n2)[N+]([O-])=O)nc1-c1ccc(Cl)cc1Cl

InChI Key: InChIKey=WVICCKVXWUMEBF-UHFFFAOYSA-N

Data: 1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50487411   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50487411 (CHEMBL427882 | CT-20026) Show SMILES CN1CCN(C(=O)C1)c1cnc(NCCNc2ccc(c(N)n2)[N+]([O-])=O)nc1-c1ccc(Cl)cc1Cl Show InChI InChI=1S/C22H23Cl2N9O3/c1-31-8-9-32(19(34)12-31)17-11-28-22(30-20(17)14-3-2-13(23)10-15(14)24)27-7-6-26-18-5-4-16(33(35)36)21(25)29-18/h2-5,10-11H,6-9,12H2,1H3,(H3,25,26,29)(H,27,28,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar	PC cid PC sid UniChem	Article	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of GSK3beta (unknown origin) expressed in Sf9 cells using GS1 as substrate and [gamma32]ATP after 30 min by scinitllation counting				Citation and Details Article DOI: 10.1007/s00044-007-9086-8 BindingDB Entry DOI: 10.7270/Q2319ZRR
					More data for this Ligand-Target Pair