BDBM50489369 CHEMBL1232930::GRL-0519

SMILES [H][C@@]12OCC[C@]1([H])[C@@]1([H])[C@H](CO[C@@]1([H])O2)OC(=O)N[C@@H](Cc1ccccc1)[C@H](O)CN(CC(C)C)S(=O)(=O)c1ccc(OC)cc1

InChI Key InChIKey=QWMNYFXRFHGYGS-DDGGWZRMSA-N

Data  7 KI

PDB links: 10 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50489369   

TargetProtease(Human immunodeficiency virus 1 (HIV-1))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50489369(CHEMBL1232930 | GRL-0519)
Affinity DataKi:  0.00600nMAssay Description:Inhibition of HIV1 proteaseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50489369(CHEMBL1232930 | GRL-0519)
Affinity DataKi:  0.5nMAssay Description:Inhibition of HIV-1 wildtype protease using Abz-Thr-Ile-Nle-p-nitro-Phe-Gln-Arg-NH2 as substrate incubated for 5 mins prior to substrate addition mea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetHIV-1 protease(Human immunodeficiency virus)
Georgia State University

Curated by ChEMBL
LigandPNGBDBM50489369(CHEMBL1232930 | GRL-0519)
Affinity DataKi:  1.20nMAssay Description:Inhibition of HIV-1 protease R8Q mutant using Abz-Thr-Ile-Nle-p-nitro-Phe-Gln-Arg-NH2 as substrate incubated for 5 mins prior to substrate addition m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetHIV-1 protease(Human immunodeficiency virus)
Georgia State University

Curated by ChEMBL
LigandPNGBDBM50489369(CHEMBL1232930 | GRL-0519)
Affinity DataKi:  3.20nMAssay Description:Inhibition of HIV-1 protease V82A mutant using Abz-Thr-Ile-Nle-p-nitro-Phe-Gln-Arg-NH2 as substrate incubated for 5 mins prior to substrate addition ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetHIV-1 protease(Human immunodeficiency virus)
Georgia State University

Curated by ChEMBL
LigandPNGBDBM50489369(CHEMBL1232930 | GRL-0519)
Affinity DataKi:  3.5nMAssay Description:Inhibition of HIV-1 protease I54M mutant using Abz-Thr-Ile-Nle-p-nitro-Phe-Gln-Arg-NH2 as substrate incubated for 5 mins prior to substrate addition ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetHIV-1 protease(Human immunodeficiency virus)
Georgia State University

Curated by ChEMBL
LigandPNGBDBM50489369(CHEMBL1232930 | GRL-0519)
Affinity DataKi:  8.90nMAssay Description:Inhibition of HIV-1 protease D30N mutant using Abz-Thr-Ile-Nle-p-nitro-Phe-Gln-Arg-NH2 as substrate incubated for 5 mins prior to substrate addition ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetHIV-1 protease(Human immunodeficiency virus)
Georgia State University

Curated by ChEMBL
LigandPNGBDBM50489369(CHEMBL1232930 | GRL-0519)
Affinity DataKi:  31nMAssay Description:Inhibition of HIV-1 protease I50V mutant using Abz-Thr-Ile-Nle-p-nitro-Phe-Gln-Arg-NH2 as substrate incubated for 5 mins prior to substrate addition ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB