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BDBM50489382 CHEMBL2311879

SMILES: Oc1ccc(Br)cc1\C=N\NC(=O)COc1ccc(Cl)cc1Cl

InChI Key: InChIKey=GQMXPWCMZUYMRP-FBCYGCLPSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50489382   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Integrase


(Human immunodeficiency virus 1)
BDBM50489382
PNG
(CHEMBL2311879)
Show SMILES Oc1ccc(Br)cc1\C=N\NC(=O)COc1ccc(Cl)cc1Cl
Show InChI InChI=1S/C15H11BrCl2N2O3/c16-10-1-3-13(21)9(5-10)7-19-20-15(22)8-23-14-4-2-11(17)6-12(14)18/h1-7,21H,8H2,(H,20,22)/b19-7+
PDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



University of Southern California

Curated by ChEMBL


Assay Description
Inhibition of wild type HIV1 integrase 3'-processing activity using 5'-end 32P-labeled linear oligonucleotide as substrate preincubated for 30 mins


Bioorg Med Chem 21: 957-63 (2013)


BindingDB Entry DOI: 10.7270/Q2WM1HBZ
More data for this
Ligand-Target Pair
Integrase


(Human immunodeficiency virus 1)
BDBM50489382
PNG
(CHEMBL2311879)
Show SMILES Oc1ccc(Br)cc1\C=N\NC(=O)COc1ccc(Cl)cc1Cl
Show InChI InChI=1S/C15H11BrCl2N2O3/c16-10-1-3-13(21)9(5-10)7-19-20-15(22)8-23-14-4-2-11(17)6-12(14)18/h1-7,21H,8H2,(H,20,22)/b19-7+
PDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



University of Southern California

Curated by ChEMBL


Assay Description
Inhibition of wild type HIV1 integrase strand transfer activity using 5'-end 32P-labeled linear oligonucleotide as substrate preincubated for 30 mins


Bioorg Med Chem 21: 957-63 (2013)


BindingDB Entry DOI: 10.7270/Q2WM1HBZ
More data for this
Ligand-Target Pair