BDBM505098 US11066404, Example 1

SMILES CC1(C)Cc2cnc(Nc3ccc(cc3)S(N)(=O)=O)nc2N(C2CCCC2)C1=O

InChI Key InChIKey=WCNNCGJVXFEBGV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 505098   

TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM505098(US11066404, Example 1)
Affinity DataIC50:  5nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged full-length CDK2/Flag-tagged cyclinE1 expressed in baculovirus expression system using eIF4E-bi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM505098(US11066404, Example 1)
Affinity DataIC50: <10nMAssay Description:CDK2/Cyclin E1 enzyme activity assays utilize full-length human CDK2 co-expressed as N-terminal GST-tagged protein with FLAG-Cyclin E1 in a baculovir...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent