BDBM505100 US11066404, Example 3

SMILES: CC1(C)Cc2cnc(NC3CCN(CC3)S(C)(=O)=O)nc2N(C1=O)c1ccccc1

InChI Key: InChIKey=POAQMSHKDCPSQM-UHFFFAOYSA-N

Data: 1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 505100   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
CDK2/CycE (Homo sapiens (Human))	BDBM505100 (US11066404, Example 3) Show SMILES CC1(C)Cc2cnc(NC3CCN(CC3)S(C)(=O)=O)nc2N(C1=O)c1ccccc1 Show InChI InChI=1S/C21H27N5O3S/c1-21(2)13-15-14-22-20(23-16-9-11-25(12-10-16)30(3,28)29)24-18(15)26(19(21)27)17-7-5-4-6-8-17/h4-8,14,16H,9-13H2,1-3H3,(H,22,23,24)	PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation US Patent					Assay Description CDK2/Cyclin E1 enzyme activity assays utilize full-length human CDK2 co-expressed as N-terminal GST-tagged protein with FLAG-Cyclin E1 in a baculovir...				US Patent US11066404 (2021)
					More data for this Ligand-Target Pair