BDBM50511632 CHEMBL4445645

SMILES C[C@H]1CN(C[C@@H](C)C1(F)F)c1ncc(Cl)c(Nc2ccc3n(C)c(=O)n(CCC(C)(C)O)c3c2)n1

InChI Key InChIKey=VFNPUAOAEFMXQI-GASCZTMLSA-N

Data  2 IC50  1 EC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50511632   

TargetB-cell lymphoma 6 protein(Homo sapiens)
TBA

Curated by ChEMBL
LigandPNGBDBM50511632(CHEMBL4445645)
Affinity DataIC50:  520nMAssay Description:Inhibition of recombinant His-tagged human BCL6 expressed in Escherichia coli BL21 AI cell incubated for 2 hrs by TR-FRET assayMore data for this Ligand-Target Pair
TargetB-cell lymphoma 6 protein(Homo sapiens)
TBA

Curated by ChEMBL
LigandPNGBDBM50511632(CHEMBL4445645)
Affinity DataEC50:  54nMAssay Description:Degradation of BCL6 in human OCI-Ly1 cells incubated for 2 hrs by MSD assayMore data for this Ligand-Target Pair
TargetB-cell lymphoma 6 protein(Homo sapiens)
TBA

Curated by ChEMBL
LigandPNGBDBM50511632(CHEMBL4445645)
Affinity DataIC50:  523nMAssay Description:Inhibition of N-terminal thioredoxin-His6 tagged human BCL6 BTB domain (5 to 129 residues) expressed in Escherichia coli BL21-AI incubated for 2 hrs ...More data for this Ligand-Target Pair