BDBM50512854 CHEMBL4468747::US11066363, Compound 37
SMILES CCc1cc2C(=O)c3c([nH]c4cc(ccc34)C#N)C(C)(C)c2cc1-c1cccc(c1)S(F)(=O)=O
InChI Key InChIKey=TWKWEBMGDALHPN-UHFFFAOYSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50512854
TargetSRSF protein kinase 1(Homo sapiens (Human))
Eberhard Karls University T£Bingen
Curated by ChEMBL
Eberhard Karls University T£Bingen
Curated by ChEMBL
Affinity DataIC50: 36nMAssay Description:Inhibition of SRPK1 (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Eberhard Karls University T£Bingen
Curated by ChEMBL
Eberhard Karls University T£Bingen
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of ALK (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 98nMAssay Description:Inhibition of SRPK2 (unknown origin) incubated for 1 hr in presence of ATP by fluorescent plate reader methodMore data for this Ligand-Target Pair
TargetSRSF protein kinase 1(Homo sapiens (Human))
Eberhard Karls University T£Bingen
Curated by ChEMBL
Eberhard Karls University T£Bingen
Curated by ChEMBL
Affinity DataIC50: 36nMAssay Description:Inhibition of SRPK1 (unknown origin) incubated for 1 hr in presence of ATP by fluorescent plate reader methodMore data for this Ligand-Target Pair
TargetSRSF protein kinase 1(Homo sapiens (Human))
Eberhard Karls University T£Bingen
Curated by ChEMBL
Eberhard Karls University T£Bingen
Curated by ChEMBL
Affinity DataIC50: 35.6nMAssay Description:SRPK1 Inhibitory Activities of the Compounds.More data for this Ligand-Target Pair