BDBM50512854 CHEMBL4468747::US11066363, Compound 37

SMILES CCc1cc2C(=O)c3c([nH]c4cc(ccc34)C#N)C(C)(C)c2cc1-c1cccc(c1)S(F)(=O)=O

InChI Key InChIKey=TWKWEBMGDALHPN-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50512854   

TargetSRSF protein kinase 1(Homo sapiens (Human))
Eberhard Karls University T£Bingen

Curated by ChEMBL
LigandPNGBDBM50512854(CHEMBL4468747 | US11066363, Compound 37)
Affinity DataIC50:  36nMAssay Description:Inhibition of SRPK1 (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Eberhard Karls University T£Bingen

Curated by ChEMBL
LigandPNGBDBM50512854(CHEMBL4468747 | US11066363, Compound 37)
Affinity DataIC50:  11nMAssay Description:Inhibition of ALK (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSRSF protein kinase 2(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50512854(CHEMBL4468747 | US11066363, Compound 37)
Affinity DataIC50:  98nMAssay Description:Inhibition of SRPK2 (unknown origin) incubated for 1 hr in presence of ATP by fluorescent plate reader methodMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSRSF protein kinase 1(Homo sapiens (Human))
Eberhard Karls University T£Bingen

Curated by ChEMBL
LigandPNGBDBM50512854(CHEMBL4468747 | US11066363, Compound 37)
Affinity DataIC50:  36nMAssay Description:Inhibition of SRPK1 (unknown origin) incubated for 1 hr in presence of ATP by fluorescent plate reader methodMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSRSF protein kinase 1(Homo sapiens (Human))
Eberhard Karls University T£Bingen

Curated by ChEMBL
LigandPNGBDBM50512854(CHEMBL4468747 | US11066363, Compound 37)
Affinity DataIC50:  35.6nMAssay Description:SRPK1 Inhibitory Activities of the Compounds.More data for this Ligand-Target Pair
In DepthDetails US Patent