BDBM50519662 CHEMBL4438748
SMILES CN(C)c1ccc(cc1)C(=O)Nc1cccc(NC(=O)COc2ccc3c(c2)occc3=O)c1
InChI Key InChIKey=WVGDUQVQWLHVEA-UHFFFAOYSA-N
Data 363 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 363 hits for monomerid = 50519662
TargetCell division cycle 7-related protein kinase/G2/mitotic-specific cyclin-B1(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant full length human CDC7/CyclinB1 using Histone H1 as substrate incubated for 120 mins in presence of [gamma-33ATP] by radiom...More data for this Ligand-Target Pair
TargetCDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant full length human CDK7/cyclinH/MAT1 using peptide substrate incubated for 40 mins in presence of [gamma-33ATP] by radiometr...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant full length human CHK1 using KKKVSRSGLYRSP as substrate incubated for 40 mins in presence of [gamma-33ATP] by radiometric s...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant full length human Pim1 using KKRNRTLTV as substrate incubated for 40 mins in presence of [gamma33P]ATP by radiometric scint...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant ALK4 (150 to end residues) using casein as substrate incubated for 40 mins in presence of [gamma-33P]ATP by radiometr...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant BMPR2 (172 to 734 residues) using myelin basic protein as substrate incubated for 120 mins in presence of [gamma-33AT...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant full length human CaMK1beta using KKLRRTLSFAEP as substrate incubated for 40 mins in presence of [gamma-33ATP] by radiometr...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant human PKCbeta1 (2 to end residues) using histone H1 as substrate incubated for 40 mins in presence of [gamma33P]ATP by radi...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant human PKCzeta (2 to end residues) using ERMRPRKRQGSVRR as substrate incubated for 40 mins in presence of [gamma33P]ATP by r...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant full-length human PRKG2 using KKLRRTLSFAEPG as substrate incubated for 40 mins in presence of [gamma33P]ATP by radiometric ...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant human SRPK2 (46 to end residues) using RSRSRSRSRSRSRSR as substrate incubated for 40 mins in presence of [gamma33P]ATP by r...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant full-length human TSSK4 using KKLNRTLSFAEPG as substrate incubated for 40 mins in presence of [gamma33P]ATP by radiometric ...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant human Ret V804M mutant (658 to end residues) using KKKVSRSGLYRSP as substrate incubated for 40 mins in presence of [gamma33...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant full length human Rsk4 using LRRASLG as substrate incubated for 40 mins in presence of [gamma33P]ATP by radiometric scintil...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant human SGK2 S416D mutant (54 to end residues) using GRPRTSSFAEGKK as substrate incubated for 40 mins in presence of [gamma33...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant human TAO1 (1 to 327 residues) using myelin basic protein as substrate incubated for 40 mins in presence of [gamma33P]ATP b...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant human VRK2 (1 to 336 residues) using casein as substrate incubated for 40 mins in presence of [gamma33P]ATP by radiometric ...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant human ZIPK (1 to 290 residues) using KKLNRTLSFAEPG substrate incubated for 40 mins in presence of [gamma33P]ATP by radiomet...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant human C-Kit D816H mutant (544 to end residues) using poly(Glu, Tyr) 4:1 as substrate incubated 40 mins in presence of [gamm...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant human DCAMKL3 (345 to end residues) using KKLNRTLSFAEPG as substrate after 40 mins in presence of [gamma-33ATP] by radiomet...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 3(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant full length human DYRK3 using RRRFRPASPLRGPP as substrate after 40 mins in presence of [gamma-33ATP] by radiometric scintil...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant full length human Fyn using KVEKIGEGTYGVV as substrate after 40 mins in presence of [gamma-33ATP] by radiometric scintillat...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant Haspin (471 to end residues) using RARTLSFAEPG as substrate after 40 mins by [gamma-33ATP] radiometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant ICK (1 to 312 residues) using RRRFRPASPLRGP as substrate after 40 mins by [gamma-33ATP] by radiometric scintillation ...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant full length human MARK4 using KKKVSRSGLYRSP as substrate incubated for 40 mins in presence of [gamma-33ATP by radiometric s...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant human MET A1209G/V1290L/Y1248D triple mutant (974 to end residues) using KKKGQEEEYVFIE as substrate incubated for 40 mins i...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant full-length human PAK3 using RRRLSFAEPG as substrate measured after 40 mins in presence of [gamma33P]ATP by radiometric sci...More data for this Ligand-Target Pair
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant human full length PDHK4 using KKKYHGHSMSDPG as substrate incubated for 40 mins in presence of [gamma33P]ATP by radiometric ...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant full length human CK2alpha2 using RRRDDDSDDD as substrate incubated 40 mins in presence of [gamma-33ATP] by radiometric sci...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant human EphA2 (596 to 900 residues) using poly(Glu, Tyr) 4:1 as substrate after 40 mins in presence of [gamma-33ATP] by radio...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant human EphB4 (561 to end residues) using poly(Glu, Tyr) 4:1 as substrate after 40 mins in presence of [gamma-33ATP] by radio...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant human FGFR3 (447 to 761 residues) using poly(Glu, Tyr) 4:1 as substrate after 40 mins in presence of [gamma-33ATP] by radio...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant IRAK1 (194 to end residues) using myelin basic protein as substrate after 40 mins by [gamma-33ATP] by radiometric sci...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant full length human LCK using KVEKIGEGTYGVV as substrate after 40 mins in presence of [gamma-33ATP] by radiometric scintillat...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant human MRCKalpha (1 to 473 residues) using KKRNRTLTV as substrate incubated for 40 mins in presence of [gamma-33ATP by radio...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant full length human mTOR/FKBP12 measured after 40 mins in presence of [gamma33P]ATP by radiometric scintillation counting ana...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant human NEK7 (2 to end residues) using FLAKSFGSPNRAYKK as substrate measured after 40 mins in presence of [gamma33P]ATP by ra...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant ABL1 (27 to end residues) using EAIYAAPFAKKK as substrate incubated for 40 mins in presence of [gamma-33P]ATP by radi...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant ABL1 M351T mutant (27 to end residues) using EAIYAAPFAKKK as substrate incubated for 40 mins in presence of [gamma-33...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant ABL1 T315I mutant (27 to end residues) using EAIYAAPFAKKK as substrate incubated for 40 mins in presence of [gamma-33...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant ACK1 (1 to 389 residues) using EFPIYDFLPAKKK as substrate incubated for 40 mins in presence of [gamma-33P]ATP by radi...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant ACTR2 (162 to end residues) using casein as substrate incubated for 120 mins in presence of [gamma-33P]ATP by radiome...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant ALK1 (142 to end residues) using casein as substrate incubated for 40 mins in presence of [gamma-33P]ATP by radiometr...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant ALK2 (147 to end residues) using casein as substrate incubated for 40 mins in presence of [gamma-33P]ATP by radiometr...More data for this Ligand-Target Pair
Target5'-AMP-activated protein kinase catalytic subunit alpha-2(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human full length AMPKalpha2 recombinant using AMARAASAAALAR as substrate incubated for 40 mins in presence of [gamma-33ATP] by radiome...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant A-Raf (273 to end residues) using myelin as substrate incubated for 40 mins in presence of [gamma-33ATP] by radiometr...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant ARK5 (2 to end residues) using KKKVSRSGLYRSP as substrate incubated for 40 mins in presence of [gamma-33ATP] by radio...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant AURORA-C (35 to end residues) using AKRRRLSSLRA as substrate incubated for 40 mins in presence of [gamma-33ATP] by ra...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant full length human BMX using poly(Glu, Tyr) 4:1 as substrate incubated for 40 mins in presence of [gamma-33ATP] by radiometr...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant human BRSK1 ( 2 to end residues) using KKKVSRSGLYRSP substrate incubated for 40 mins in presence of [gamma-33ATP] by radiom...More data for this Ligand-Target Pair