BDBM50523287 CHEMBL4447565

SMILES O=C1NC(=S)S\C1=C/c1ccc(OCC#C)cc1

InChI Key InChIKey=QREKGPHPIGGKCE-FLIBITNWSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50523287   

TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Alexandria University

Curated by ChEMBL
LigandPNGBDBM50523287(CHEMBL4447565)
Affinity DataIC50:  1.16E+4nMAssay Description:Inhibition of ovine COX1 catalytic activity using arachidonic acid as substrate pre-incubated for 10 mins followed by substrate addition and measured...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Alexandria University

Curated by ChEMBL
LigandPNGBDBM50523287(CHEMBL4447565)
Affinity DataIC50:  120nMAssay Description:Inhibition of human recombinant COX2 catalytic activity using arachidonic acid as substrate pre-incubated for 10 mins followed by substrate addition ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed