BDBM50523652 CHEMBL4445368::US10709709, Example 89

SMILES Cc1ncnc2n(ccc12)[C@@H]1C[C@H](Oc2cc(Br)cc3CCNCc23)[C@@H](O)[C@H]1O

InChI Key InChIKey=GZUFPFJUTPPVMC-BTHPGYMESA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50523652   

TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Prelude Therapeutics

Curated by ChEMBL
LigandPNGBDBM50523652(CHEMBL4445368 | US10709709, Example 89)
Affinity DataIC50:  1nMAssay Description:Inhibition of PRMT5 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Prelude Therapeutics

Curated by ChEMBL
LigandPNGBDBM50523652(CHEMBL4445368 | US10709709, Example 89)
Affinity DataIC50:  1nMAssay Description:Compounds were solubilized in DMSO and serially diluted, using 3-fold dilutions, into 100% DMSO at a concentration 50-fold greater than the desired a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent