BDBM50526314 CHEMBL4459692::US10752616, Code No. BHBA-001

SMILES Cc1ccc(C)c2oc(cc12)-c1nc(no1)-c1ccc(cc1)C(O)=O

InChI Key InChIKey=AVCXUODHLRZJJP-UHFFFAOYSA-N

Data  5 IC50  7 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50526314   

TargetRetinoic acid receptor beta(Human)
King''S College London

US Patent
LigandPNGBDBM50526314(CHEMBL4459692 | US10752616, Code No. BHBA-001)
Affinity DataEC50:  1.94nMAssay Description:Transcriptional transactivation assays were performed with gal4 fusion receptor constructs, created using each of the RAR ligand binding domains of e...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetRetinoic acid receptor alpha(Human)
King''S College London

US Patent
LigandPNGBDBM50526314(CHEMBL4459692 | US10752616, Code No. BHBA-001)
Affinity DataEC50:  26nMAssay Description:Transcriptional transactivation assays were performed with gal4 fusion receptor constructs, created using each of the RAR ligand binding domains of e...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetRetinoic acid receptor gamma(Human)
King''S College London

US Patent
LigandPNGBDBM50526314(CHEMBL4459692 | US10752616, Code No. BHBA-001)
Affinity DataEC50:  11nMAssay Description:Transcriptional transactivation assays were performed with gal4 fusion receptor constructs, created using each of the RAR ligand binding domains of e...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetCytochrome P450 2C19(Human)
King'S College

Curated by ChEMBL
LigandPNGBDBM50526314(CHEMBL4459692 | US10752616, Code No. BHBA-001)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of CYP2C19 in human liver microsomes by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor beta(Human)
King''S College London

US Patent
LigandPNGBDBM50526314(CHEMBL4459692 | US10752616, Code No. BHBA-001)
Affinity DataEC50:  2.10nMAssay Description:Transactivation of GAL4 DBD-fused human RARbeta-LBD expressed in HEK293 cells by beta-lactamase reporter gene based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Human)
King'S College

Curated by ChEMBL
LigandPNGBDBM50526314(CHEMBL4459692 | US10752616, Code No. BHBA-001)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsomes by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor gamma(Mouse)
King'S College

Curated by ChEMBL
LigandPNGBDBM50526314(CHEMBL4459692 | US10752616, Code No. BHBA-001)
Affinity DataEC50:  13nMAssay Description:Transactivation of GAL4-fused mouse RARgamma-LBD expressed in COS-7 cells after 24 hrs by bright-Glo reagent based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Human)
King'S College

Curated by ChEMBL
LigandPNGBDBM50526314(CHEMBL4459692 | US10752616, Code No. BHBA-001)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of CYP1A2 in human liver microsomes by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Human)
King'S College

Curated by ChEMBL
LigandPNGBDBM50526314(CHEMBL4459692 | US10752616, Code No. BHBA-001)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of CYP2C9 in human liver microsomes by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Human)
King'S College

Curated by ChEMBL
LigandPNGBDBM50526314(CHEMBL4459692 | US10752616, Code No. BHBA-001)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of CYP2D6 in human liver microsomes by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor beta(Mouse)
King'S College

Curated by ChEMBL
LigandPNGBDBM50526314(CHEMBL4459692 | US10752616, Code No. BHBA-001)
Affinity DataEC50:  1.90nMAssay Description:Transactivation of GAL4-fused mouse RARbeta-LBD expressed in COS-7 cells after 24 hrs by bright-Glo reagent based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor alpha(Mouse)
King'S College

Curated by ChEMBL
LigandPNGBDBM50526314(CHEMBL4459692 | US10752616, Code No. BHBA-001)
Affinity DataEC50:  26nMAssay Description:Transactivation of GAL4-fused mouse RARalpha-LBD expressed in COS-7 cells after 24 hrs by bright-Glo reagent based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed