BDBM50527133 CHEMBL4569080

SMILES Nc1nc(nc2n(cnc12)[C@@H]1O[C@H](COP(O)(=O)CP(O)(O)=O)[C@@H](O)[C@H]1O)N1CCNCC1

InChI Key InChIKey=GUHCLCYLXMLIOC-IDTAVKCVSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50527133   

Target5'-nucleotidase(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50527133(CHEMBL4569080)
Affinity DataKi:  184nMAssay Description:Inhibition of purified recombinant soluble human CD73 expressed in Sf9 cells [3H]AMP as substrate incubated for 25 mins by scintillation counting met...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5'-nucleotidase(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50527133(CHEMBL4569080)
Affinity DataKi:  238nMAssay Description:Inhibition of native CD73 in human MDA-MB-231 cell membrane preparations [3H]AMP as substrate incubated for 25 mins by scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5'-nucleotidase(Rat)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50527133(CHEMBL4569080)
Affinity DataKi:  2.29E+3nMAssay Description:Inhibition of purified recombinant soluble rat CD73 expressed in Sf9 cells [3H]AMP as substrate incubated for 25 mins by scintillation counting metho...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed