BDBM50528533 CHEMBL4558430

SMILES Cc1cn(cn1)-c1cc(NC(=O)c2ccc3C[C@H](Cc3c2)Nc2cncnc2)cc(c1)C(F)(F)F

InChI Key InChIKey=XFLAQLCDMJRPFH-HXUWFJFHSA-N

Data  5 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50528533   

TargetEpithelial discoidin domain-containing receptor 1(Homo sapiens (Human))
Jinan University

Curated by ChEMBL
LigandPNGBDBM50528533(CHEMBL4558430)
Affinity DataIC50:  5.60nMAssay Description:Inhibition of GST-tagged recombinant human DDR1 (440 to 876 amino acids) expressed in baculovirus using fluorescein-poly GAT as substrate after 1 hr ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetNT-3 growth factor receptor(Homo sapiens (Human))
Jinan University

Curated by ChEMBL
LigandPNGBDBM50528533(CHEMBL4558430)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of His-tagged human TrkC expressed in baculovirus expression system using Tyr1 peptide as substrate after 1.5 hrs by FRET-based Z-LYTE ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetBDNF/NT-3 growth factors receptor(Homo sapiens (Human))
Jinan University

Curated by ChEMBL
LigandPNGBDBM50528533(CHEMBL4558430)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of His-tagged human TrkB expressed in baculovirus expression system using Tyr1 peptide as substrate after 1.5 hrs by FRET-based Z-LYTE ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetDiscoidin domain-containing receptor 2(Homo sapiens (Human))
Jinan University

Curated by ChEMBL
LigandPNGBDBM50528533(CHEMBL4558430)
Affinity DataIC50:  22nMAssay Description:Inhibition of GST-tagged recombinant human DDR2 expressed in baculovirus using fluorescein-poly GAT as substrate after 1 hr by FRET-based LanthaScree...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Jinan University

Curated by ChEMBL
LigandPNGBDBM50528533(CHEMBL4558430)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of His-tagged human TrkA expressed in baculovirus expression system using Tyr1 peptide as substrate after 1.5 hrs by FRET-based Z-LYTE ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed