BDBM50528938 CHEMBL4551599

SMILES Nc1nc2[nH]cc(Cc3ccc(\C=C\c4ccccc4C(O)=O)cc3)c2c(=O)[nH]1

InChI Key InChIKey=QXLUOILIYGLPRE-MDZDMXLPSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50528938   

TargetPolyunsaturated fatty acid lipoxygenase ALOX15B(Rattus norvegicus)
Yale University

Curated by ChEMBL
LigandPNGBDBM50528938(CHEMBL4551599)
Affinity DataIC50:  7.30E+3nMAssay Description:Inhibition of recombinant human His6-tagged TS using dUMP and 5,10-methylenetetrahydrofolate as substrate by spectrometryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Cryptosporidium hominis)
Yale University

Curated by ChEMBL
LigandPNGBDBM50528938(CHEMBL4551599)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of recombinant Cryptosporidium hominis TS-DHFR expresssed in Escherichia coli PA414 using dUMP and 5,10-methylenetetrahydrofolate as subst...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed