BDBM50528947 CHEMBL4445927

SMILES COc1ccc(CC(O)=O)c(NC(=O)c2ccc(Cc3c[nH]c4nc(N)[nH]c(=O)c34)cc2)c1

InChI Key InChIKey=UOZOJZZNBFZRTI-UHFFFAOYSA-N

Data  2 IC50

PDB links: 2 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50528947   

TargetPolyunsaturated fatty acid lipoxygenase ALOX15B(Rattus norvegicus)
Yale University

Curated by ChEMBL
LigandPNGBDBM50528947(CHEMBL4445927)
Affinity DataIC50:  800nMAssay Description:Inhibition of recombinant human His6-tagged TS using dUMP and 5,10-methylenetetrahydrofolate as substrate by spectrometryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Cryptosporidium hominis)
Yale University

Curated by ChEMBL
LigandPNGBDBM50528947(CHEMBL4445927)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of recombinant Cryptosporidium hominis TS-DHFR expresssed in Escherichia coli PA414 using dUMP and 5,10-methylenetetrahydrofolate as subst...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB