BDBM50531580 CHEMBL4448501

SMILES OCC[C@H]1COc2cc(F)c(CC3CCCCC3)cc2N1C(=O)c1ccc2OCC(=O)Nc2c1

InChI Key InChIKey=CBUBLNUCASPVJQ-IBGZPJMESA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50531580   

TargetMineralocorticoid receptor(Homo sapiens (Human))
Pharmaron-Beijing

Curated by ChEMBL
LigandPNGBDBM50531580(CHEMBL4448501)
Affinity DataKi:  10nMAssay Description:Displacement of [3H]-aldosterone to human mineralocorticoid receptor LBD by radiometric binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Pharmaron-Beijing

Curated by ChEMBL
LigandPNGBDBM50531580(CHEMBL4448501)
Affinity DataKi:  200nMAssay Description:Binding affinity to recombinant human GR LBD by fluormone GS red-fluorescence polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Pharmaron-Beijing

Curated by ChEMBL
LigandPNGBDBM50531580(CHEMBL4448501)
Affinity DataIC50:  251nMAssay Description:Antagonist activity at gal4-fused human mineralocorticoid receptor LBD expressed in UAS-MR-bla HEK293 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed