BDBM50531589 CHEMBL4468672

SMILES CC(C)C[C@H]1COc2cc(F)ccc2N1C(=O)c1ccc2OCC(=O)Nc2c1

InChI Key InChIKey=CERMKIOTMWNAGM-HNNXBMFYSA-N

Data  3 KI  1 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50531589   

TargetMineralocorticoid receptor(Homo sapiens (Human))
Pharmaron-Beijing

Curated by ChEMBL
LigandPNGBDBM50531589(CHEMBL4468672)
Affinity DataKi:  2nMAssay Description:Displacement of [3H]-aldosterone to human mineralocorticoid receptor LBD by radiometric binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetGlucocorticoid receptor(Homo sapiens (Human))
Pharmaron-Beijing

Curated by ChEMBL
LigandPNGBDBM50531589(CHEMBL4468672)
Affinity DataKi:  50nMAssay Description:Binding affinity to recombinant human GR LBD by fluormone GS red-fluorescence polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Pharmaron-Beijing

Curated by ChEMBL
LigandPNGBDBM50531589(CHEMBL4468672)
Affinity DataKi:  2.51E+3nMAssay Description:Binding affinity to recombinant human progesterone receptor LBD by fluormone PL red-fluorescence polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Pharmaron-Beijing

Curated by ChEMBL
LigandPNGBDBM50531589(CHEMBL4468672)
Affinity DataIC50:  63nMAssay Description:Antagonist activity at gal4-fused human mineralocorticoid receptor LBD expressed in UAS-MR-bla HEK293 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB