BDBM50540086 CHEMBL4646965::US11026937, Compound I-103

SMILES O=C(\C=C\c1nc2ccccc2[nH]1)c1c(-c2ccccc2)c2ccccc2[nH]c1=O

InChI Key InChIKey=JMHGWNZBVSPKBH-CCEZHUSRSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50540086   

TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Qilu University Of Technology (Shandong Academy Of Sciences)

Curated by ChEMBL
LigandPNGBDBM50540086(CHEMBL4646965 | US11026937, Compound I-103)
Affinity DataIC50:  1.64E+3nMAssay Description:Inhibition of PKBalpha (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-beta serine/threonine-protein kinase(Homo sapiens (Human))
Qilu University Of Technology (Shandong Academy Of Sciences)

Curated by ChEMBL
LigandPNGBDBM50540086(CHEMBL4646965 | US11026937, Compound I-103)
Affinity DataIC50:  1.64E+3nMAssay Description:Inhibition of PKBbeta (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-arginine deiminase type-4(Homo sapiens (Human))
Padlock Therapeutics

US Patent
LigandPNGBDBM50540086(CHEMBL4646965 | US11026937, Compound I-103)
Affinity DataIC50:  7.00E+4nMAssay Description:Assay buffer (as aforementioned): 100 mM Tris-HCl (pH 7.6), 2 mM DTT, 1 mM CaCl2Final concentrations:100 nM hPAD4 enzyme50 μM (8-fold sub-Km) su...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetInhibitor of nuclear factor kappa-B kinase subunit alpha(Homo sapiens (Human))
Qilu University Of Technology (Shandong Academy Of Sciences)

Curated by ChEMBL
LigandPNGBDBM50540086(CHEMBL4646965 | US11026937, Compound I-103)
Affinity DataIC50:  1.64E+3nMAssay Description:Inhibition of IKKalpha (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Qilu University Of Technology (Shandong Academy Of Sciences)

Curated by ChEMBL
LigandPNGBDBM50540086(CHEMBL4646965 | US11026937, Compound I-103)
Affinity DataIC50:  1.64E+3nMAssay Description:Inhibition of IKKbeta (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-gamma serine/threonine-protein kinase(Homo sapiens (Human))
Qilu University Of Technology (Shandong Academy Of Sciences)

Curated by ChEMBL
LigandPNGBDBM50540086(CHEMBL4646965 | US11026937, Compound I-103)
Affinity DataIC50:  1.64E+3nMAssay Description:Inhibition of PKBgamma (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed