BDBM50540352 CHEMBL4643164::US11427590, Entry 13

SMILES CC(=O)N[C@@H]1CCN(C1)c1cc(C)nn2c(c(C)nc12)-c1cccs1

InChI Key InChIKey=KBAHWLBOZCNRIT-CQSZACIVSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50540352   

TargetSphingomyelin phosphodiesterase 3(Homo sapiens)
The Johns Hopkins University

US Patent
LigandPNGBDBM50540352(CHEMBL4643164 | US11427590, Entry 13)
Affinity DataIC50:  300nMAssay Description:The fluorescence based assay to monitor the activity of human nSMase2 in the presence or absence of potential inhibitors has been described recently....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSphingomyelin phosphodiesterase 3(Homo sapiens)
The Johns Hopkins University

US Patent
LigandPNGBDBM50540352(CHEMBL4643164 | US11427590, Entry 13)
Affinity DataIC50:  300nMAssay Description:Inhibition of human recombinant full-length nSMase expressed in HEK293 cells using sphingomyelin as substrate measured after 1 hr by alkaline phospha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed