BDBM50541448 CHEMBL4633785

SMILES [H][C@@]12C[C@]1([H])c1ccc(F)c(C(O)=O)c1OB2O

InChI Key InChIKey=KOHUFVUIYUCFNG-PHDIDXHHSA-N

Data  3 KI  16 IC50

PDB links: 2 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 19 hits for monomerid = 50541448   

TargetOXA23 carbapenemase(Acinetobacter baumannii)
Qpex Biopharma

Curated by ChEMBL
LigandPNGBDBM50541448(CHEMBL4633785)
Affinity DataKi:  0.740nMAssay Description:Inhibition of Acinetobacter baumannii OXA-23 using nitrocefin as substrate preincubated for 10 mins followed by substrate addition measured every 10 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbapenem-hydrolyzing beta-lactamase KPC()
Qpex Biopharma

Curated by ChEMBL
LigandPNGBDBM50541448(CHEMBL4633785)
Affinity DataKi:  1.90nMAssay Description:Inhibition of recombinant Escherichia coli KPC-2 using nitrocefin as substrate preincubated for 10 mins followed by substrate addition and measured e...More data for this Ligand-Target Pair
TargetVIM-1 metallo-beta-lactamase(Klebsiella pneumoniae)
Qpex Biopharma

Curated by ChEMBL
LigandPNGBDBM50541448(CHEMBL4633785)
Affinity DataKi:  8nMAssay Description:Inhibition of recombinant Escherichia coli VIM-1 using nitrocefin as substrate preincubated for 10 mins followed by substrate addition measured every...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Qpex Biopharma

Curated by ChEMBL
LigandPNGBDBM50541448(CHEMBL4633785)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of mammalian MMP-1 (unknown origin) using McaPLGLDpaAR-NH2 as substrate preincubated for 10 mins followed by substrate addition measured a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Qpex Biopharma

Curated by ChEMBL
LigandPNGBDBM50541448(CHEMBL4633785)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of mammalian MMP-9 (unknown origin) using McaPLGLDpaAR-NH2 as substrate preincubated for 10 mins followed by substrate addition measured a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen B2(Homo sapiens)
Qpex Biopharma

Curated by ChEMBL
LigandPNGBDBM50541448(CHEMBL4633785)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of mammalian chymotrypsin (unknown origin) using Suc-AAPF-AMC as substrate preincubated for 10 mins followed by substrate addition measure...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Qpex Biopharma

Curated by ChEMBL
LigandPNGBDBM50541448(CHEMBL4633785)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of mammalian thrombin (unknown origin) using Benz-FVR-AMC as substrate preincubated for 10 mins followed by substrate addition measured af...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Qpex Biopharma

Curated by ChEMBL
LigandPNGBDBM50541448(CHEMBL4633785)
Affinity DataIC50:  1.32E+5nMAssay Description:Inhibition of mammalian neutrophil elastase (unknown origin) using MeOSuc-AAVP-AMC as substrate preincubated for 10 mins followed by substrate additi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypsin(Homo sapiens (Human))
Qpex Biopharma

Curated by ChEMBL
LigandPNGBDBM50541448(CHEMBL4633785)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of mammalian trypsin (unknown origin) using N-Bz-R-AMC as substrate preincubated for 10 mins followed by substrate addition measured after...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Qpex Biopharma

Curated by ChEMBL
LigandPNGBDBM50541448(CHEMBL4633785)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of mammalian plasmin (unknown origin) using H-D-VLK-pNA as substrate preincubated for 10 mins followed by substrate addition measured afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Qpex Biopharma

Curated by ChEMBL
LigandPNGBDBM50541448(CHEMBL4633785)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of mammalian urokinase (unknown origin) using NGK-pNA as substrate preincubated for 10 mins followed by substrate addition measured after ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymase(Homo sapiens (Human))
Qpex Biopharma

Curated by ChEMBL
LigandPNGBDBM50541448(CHEMBL4633785)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of mammalian chymase (unknown origin) using Suc-AAPF-AMC as substrate preincubated for 10 mins followed by substrate addition measured aft...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 2(Homo sapiens (Human))
Qpex Biopharma

Curated by ChEMBL
LigandPNGBDBM50541448(CHEMBL4633785)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of mammalian DPP7 (unknown origin) using H-Lys-Pro-AMC as substrate preincubated for 10 mins followed by substrate addition measured after...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 8(Homo sapiens (Human))
Qpex Biopharma

Curated by ChEMBL
LigandPNGBDBM50541448(CHEMBL4633785)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of mammalian DPP8 (unknown origin) using Lys-Pro-AMC as substrate preincubated for 10 mins followed by substrate addition measured after 3...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 9(Homo sapiens (Human))
Qpex Biopharma

Curated by ChEMBL
LigandPNGBDBM50541448(CHEMBL4633785)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of mammalian DPP9 (unknown origin) using Lys-Pro-AMC as substrate preincubated for 10 mins followed by substrate addition measured after 3...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme 2(Homo sapiens (Human))
Qpex Biopharma

Curated by ChEMBL
LigandPNGBDBM50541448(CHEMBL4633785)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of mammalian ACE-2 (unknown origin) using Mca-APK(Dnp) as substrate preincubated for 10 mins followed by substrate addition measured after...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin G(Homo sapiens (Human))
Qpex Biopharma

Curated by ChEMBL
LigandPNGBDBM50541448(CHEMBL4633785)
Affinity DataIC50:  6.66E+5nMAssay Description:Inhibition of mammalian cathepsin G (unknown origin) using Suc-AAPF-AMC as substrate preincubated for 10 mins followed by substrate addition measured...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCatalase(Homo sapiens (Human))
Qpex Biopharma

Curated by ChEMBL
LigandPNGBDBM50541448(CHEMBL4633785)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of mammalian cathepsin A (unknown origin) using MCA-RPPGFSAFK-Dnp as substrate preincubated for 10 mins followed by substrate addition mea...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
Qpex Biopharma

Curated by ChEMBL
LigandPNGBDBM50541448(CHEMBL4633785)
Affinity DataIC50:  4.31E+5nMAssay Description:Inhibition of mammalian ECE-1 (unknown origin) using MCA-RPPGFSAFK(DNP)-OH as substrate preincubated for 10 mins followed by substrate addition measu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed