BDBM50543 3-[(3-chloro-1,4-diketo-2-naphthyl)amino]benzoic acid::3-[(3-chloro-1,4-dioxo-1,4-dihydronaphthalen-2-yl)amino]benzoic acid::3-[(3-chloro-1,4-dioxo-2-naphthalenyl)amino]benzoic acid::3-[(3-chloro-1,4-dioxonaphthalen-2-yl)amino]benzoic acid::3-[[3-chloranyl-1,4-bis(oxidanylidene)naphthalen-2-yl]amino]benzoic acid::MLS000689606::SMR000312850::cid_470958

SMILES OC(=O)c1cccc(NC2=C(Cl)C(=O)c3ccccc3C2=O)c1

InChI Key InChIKey=TYLPTGMQARBNQU-UHFFFAOYSA-N

Data  3 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50543   

TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Emory University

Curated by PubChem BioAssay
LigandPNGBDBM50543(3-[(3-chloro-1,4-diketo-2-naphthyl)amino]benzoic a...)
Affinity DataIC50:  3.66E+3nMAssay Description:NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Nikolovska-Coleska, Univer...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
Montana State University

Curated by ChEMBL
LigandPNGBDBM50543(3-[(3-chloro-1,4-diketo-2-naphthyl)amino]benzoic a...)
Affinity DataIC50:  2.43E+4nMAssay Description:Inhibition of recombinant Cdc25B (unknown origin) using OMFP as substrate measured every 30 sec for 10 mins by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 1(Homo sapiens (Human))
Montana State University

Curated by ChEMBL
LigandPNGBDBM50543(3-[(3-chloro-1,4-diketo-2-naphthyl)amino]benzoic a...)
Affinity DataIC50:  3.29E+4nMAssay Description:Inhibition of recombinant Cdc25A (unknown origin) using OMFP as substrate measured every 30 sec for 10 mins by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity mitogen-activated protein kinase kinase 7(Homo sapiens (Human))
Montana State University

Curated by ChEMBL
LigandPNGBDBM50543(3-[(3-chloro-1,4-diketo-2-naphthyl)amino]benzoic a...)
Affinity DataKd:  1.90E+3nMAssay Description:Binding affinity to MKK7 (unknown origin) expressed in HEK293 cells assessed as dissociation constant by kinomescan methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed