BDBM50545524 CHEMBL2369159

SMILES NC(=N)N\N=C\c1cccc(Cl)c1Cl

InChI Key InChIKey=WLTSTDGGFCQWTK-YIXHJXPBSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50545524   

TargetProtein phosphatase 1 regulatory subunit 15A(Homo sapiens)
Cedilla Therapeutics

Curated by ChEMBL
LigandPNGBDBM50545524(CHEMBL2369159)
Affinity DataIC50:  977nMAssay Description:Inhibition of amino-terminal MBP-tagged/carboxy-terminal His6-tagged human PPP1R15A (325 to 626 residues)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMaternal embryonic leucine zipper kinase(Homo sapiens (Human))
Cedilla Therapeutics

Curated by ChEMBL
LigandPNGBDBM50545524(CHEMBL2369159)
Affinity DataIC50:  200nMAssay Description:Inhibition of MELK (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein phosphatase 1 regulatory subunit 15B(Homo sapiens)
Cedilla Therapeutics

Curated by ChEMBL
LigandPNGBDBM50545524(CHEMBL2369159)
Affinity DataIC50:  33nMAssay Description:Inhibition of amino-terminal MBP-tagged/carboxy-terminal His6-tagged human PPP1R15B (325 to 626 residues)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed